产品描述 

塔望科技提供全系列的动物实验用低/高氧控制产品，包括恒定浓度控制的低氧动物箱、高氧动物箱、可编程的间歇氧浓度控制系统、带缓冲舱的手套低氧箱等。整套低氧/高氧实验箱装置主要由氧气控制器和动物实验箱两部分组成。另可提供多种不同的气体控制器，满足不同实验O₂、CO₂、NO、CO、O₃等气体浓度控制的需求。

该款氧浓度实验系统是在Ox-100基础上升级而来，特色功能如下：

低氧、高氧精准控制：

提供低氧及高氧控制不同的型号，控制精准，控制误差≤0.1%

不同笼不同位置之间经过严格验证，保证浓度均匀性

恒温功能

避免不同季节气温变化影响实验，可加热和制冷；

智能除CO₂

系统内增加了自动去除CO2功能，使实验条件更加科学，节省了气体用量。

数据存储

数据实时存储到U盘，实现数据可追溯性。

视频监控

远程视频监控，随时随地查看实验状态

紫外灭菌

实验完成可进行紫外灭菌，除异味，保证动物实验的清洁环境

低氧饲养一站式，无需取放动物

低氧实验完毕，直接开启饲养环境，无需频繁取放动物

动物低氧实验系统提供不同尺寸的动物低氧箱，默认低氧箱可放置2个大鼠笼（或4个小鼠笼），同时提供大号规格，可容纳4个大鼠笼和8个大鼠笼。如需其它规格，可提供定制。

应用领域

肺动脉高压、肾脏疾病研究、肿瘤研究、心血管疾病研究、视网膜病变、运动医学研究、OSAHS、脑发育与神经生物学、干细胞研究、医学研究等。

相关文献

[1]Ma Jinqiu,Wang Chen yun,Sun Yunbo,Pang Lulu,Zhu Siqing,Liu Yijing,Zhu Lin,Zhang Shouguo,Wang Lin,Du Lina."Comparative study of oral and intranasal puerarin for prevention of brain injury induced by acute high-altitude hypoxia".[J] International Journal of Pharmaceutics,2020,591.

[2]Guijuan Chen,Kang Cheng,Yun Niu,Li Zhu,Xueting Wang."Epicatechin gallate prevents inflammatory response in hypoxia-activated microglia and cerebral edema by inhibiting NF-κB signaling".[J]. Archives of Biochemistry and Biophysics,Volume 729,109393.

[3]Ya peng,Lu PanpanChang,Wang wangDing,Jiang peiBian,Dan Wang,Xue tingWang,Qian qianLuo,Xiao meiWu,Li Zhu."Pharmacological inhibition of mitochondrial division attenuates simulated high-altitude exposure-induced cerebral edema in mice:Involvement of inhibition of the NF-κB signaling pathway in glial cells".[J].European Journal of Pharmacology,Volume 929,2022,175137.

[4]Jun-Yu Wei,Miao-Yue Hu,Xiu-Qi Chen,Feng-Ying Lei,Jin-Shuang Wei,Jie Chen,Xuan-Kai Qin & Yuan-Han Qin."Rosiglitazone attenuates hypoxia-induced renal cell apoptosis by inhibiting NF-κB signaling pathway in a PPARγ-dependent manner".[J].European Journal of Pharmacology,Renal Failure,44:1,2056-2065.

[5]Yilan Wang,Zhe ruiShen, Caixia Pei,Si jing Zhao, Nan Jia,De meiHuang, Xiao minWang,Yongcan Wu,Shi huaShi, Ya congHe, Zhen xing Wang,"Eleutheroside B ameliorated high altitude pulmonary edema by attenuating ferroptosis and necroptosis through Nrf2-antioxidant response signaling".[J]. Biomedicine & Pharmacotherapy, Volume 156,2022,113982.

[6]Fang Zhao,Yan Meng, Yue Wang,Siqi Fan, Yu Liu,Xiangfeng Zhang, Chenyang Ran, Hongxin Wang and Meili Lu. "Protective effect of Astragaloside IV on chronic intermittent hypoxia-induced vascular endothelial dysfunction through the calpain-1/SIRT1/AMPK signaling pathway".[J]. Frontiers in Pharmacology,10.3389/fphar.2022.920977.

[7]Xu Y,Kong X,Li J,Cui T,Wei Y,Xu J,hu Y,Zhu X."Mild Hypoxia Enhances the Expression of HIF and VEGF and Triggers the Response to Injury in Rat Kidneys."[J]. Front. Physiol.12:690496. doi: 10.3389/fphys.2021.690496.

[8]Liang Xie, Qinhan Wu, Weiping Hu, Xu Wu, Guiling Xiang, Shengyu Hao, Han Guo, Shanqun Li."Impact of histaminergic H3 receptor antagonist on hypoglossal nucleus in chronic intermittent hypoxia conditions."[J].Psychopharmacology.

[9]Li Huang, Tian youLi, Min Zhou, Meng yanDeng, Li dongZhang, Long Yi, Jun dongZhu, Xiao huiZhu, Mantian Mi. "Hypoxia Improves Endurance Performance by Enhancing Short Chain Fatty Acids Production via Gut Microbiota Remodeling."[J]. Front. Microbiol.12:820691.

[10]Yanhong Pei a b, Lifei Huang c, Tong Wang c, Qinhan Yao a, Yanrong Sun a, Yan Zhang a, Xiaomei Yang a, Jiliang Zhai d, Lihua Qin a, Jiajia Xue c, Xing Wang c, Hongquan Zhang a b, Junhao Yan."Bone marrow mesenchymal stem cells loaded into hydrogel/nanofiber composite scaffolds ameliorate ischemic brain injury. materialstoday ADVANCES, Volume 17, March 2023, 100349.

[11]Zhang, C.,Sun, Y., Guo, Y.et al."JMJD1C promotes smooth muscle cell proliferation by activating glycolysis in pulmonary arterial hypertension."[J].Cell Death Discov.9,98(2023).

[12]Chenyu Xu, Jun Xu, Chunfang Zou, Qian Li, Shan Mao, Ying Shi, Yan Tan, Wei Gu, Liang Ye."Chronic Intermittent Hypoxia Regulates CaMKII-Dependent MAPK Signaling to Promote the Initiation of Abdominal Aortic Aneurysm."[J]. Hindawi, Oxidative Medicine and Cellular Longevity Volume 2021, Article ID 2502324, 15 pages.

[13]Jing Zhang, Jian-Zhong Jiang, Jun Xu, Chen-Yu Xu, Shan Mao, Ying Shi, Wei Gu, Chun-Fang Zou, Yue-Ming Zhao,Liang Ye. "Identification of Novel Biomarkers for Abdominal Aortic Aneurysm Promoted by Obstructive Sleep Apnea."[J].Elsevier Inc. This is an open access article under the CC BY-NC-ND license.

[14]Zhang Q,Xu L,Bai Y,Chen P,Xing M,Cai F,Wu Y,Song W."Intermittent hypoxia-induced enhancement of sociability and working memory associates with CNTNAP2 upregulation."[J].Front. Mol.Neurosci.16:1155047.

[15]Chen Zhang, Yue Sun, Yingying Guo, Jingjing Xu, Haiyan Zhao."JMJD1C promotes smooth muscle cell proliferation by activating glycolysis in pulmonary arterial hypertension."[J]. Cell Death Discovery (2023) 9:98.

[16]Ailin Yang, Lifei Guo, Yanfang Zhang, Chenjin Qiao, Yijin Wang, Jiaying Li, Min Wang, Jinliang Xing, Fei Li, Lele Ji, Haitao Guo, Ru Zhang,MFN2-mediated mitochondrial fusion facilitates acute hypobaric hypoxia-induced cardiac dysfunction by increasing glucose catabolism and ROS production,Biochimica et Biophysica Acta (BBA) - General Subjects,Volume 1867, Issue 9,2023,130413,ISSN 0304-4165.

[17]Eleutheroside E from pre-treatment of Acanthopanax senticosus (Rupr. etMaxim.) Harms ameliorates high-altitude-induced heart injury by regulating NLRP3-N Jia, Z Shen,S Zhao,Y Wang, C Pei, D Huang - International , 2023 - Elsevier… The rats were placed in a hypobaric hypoxia chamber (ProOx-830, Tow-Int Tech, Shanghai,China) to mimic the environment of high-altitude hypobaric hypoxic. After the rats were.

[18]Nan Jia, Zherui Shen, Sijing Zhao, Yilan Wang, Caixia Pei, Demei Huang, Xiaomin Wang, Yongcan Wu, Shihua Shi, Yacong He, Zhenxing Wang,Eleutheroside E from pre-treatment of Acanthopanax senticosus (Rupr.etMaxim.) Harms ameliorates high-altitude-induced heart injury by regulating NLRP3 inflammasome-mediated pyroptosis via NLRP3/caspase-1 pathway,International Immunopharmacology,Volume 121,2023,110423,ISSN 1567-5769.

[19]AUTHOR=Long Yanrong, Chen Hongbin, Deng Junchao, Ning Junjie, Yang Pengbo, Qiao Lina, Cao Zhongwei,TITLE=Deficiency of endothelial FGFR1 alleviates hyperoxia-induced bronchopulmonary dysplasia in neonatal mice ，JOURNAL=Frontiers in Pharmacology VOLUME=13 YEAR=2022 DOI=10.3389/fphar.2022.1039103 ，The chamber contained a continuous oxygen monitoring system (ProOX-100HE,TOW-INTTECH). 

[20]Haimei Lun, Ruochuan Liu, Qiao Hu, Yaoli Liu, Lisi Wei, Xia Liu, Dan Wu, Shangyong Zhu,Contrast Enhanced Ultrasonography of Kidney in Chronic Intermittent Hypoxia Rat Model,[J]Journal of Ultrasound in Medicine,2022-12-07,DOI:10.1002/jum.16147.

[21]Chen YuJiang,Li WeiWu,Yi WeiLiu,Bei Feng, Lin-Cai Ye,Xu Huang,Yang-Yang He,Yi Shen, Yi-Fan Zhu, Xing-Liang Zhou, Dai-Ji Jiang, Hai-Kun Qi, Hao Zhang, and Yi Yan.Identification of ACKR4 as an immune checkpoint in pulmonary arterial hypertension,[J]Frontiers in Immunology,28 June 2023,Volume 14 - 2023,DOI:10.3389/fimmu.2023.1153573.

[22]Pan Z, Yao Y, Liu X, et al. Nr1d1 inhibition mitigates intermittent hypoxia-induced pulmonary hypertension via Dusp1-mediated Erk1/2 deactivation and mitochondrial fission attenuation[J]. Cell Death Discovery, 2024, 10(1): 459.

[23]Song J, Zheng J, Li Z, et al. Sulfur dioxide inhibits mast cell degranulation by sulphenylation of galectin-9 at cysteine 74[J]. Frontiers in Immunology, 2024, 15: 1369326.

[24]Zhou Z, Zhao Q, Huang Y, et al. Berberine ameliorates chronic intermittent hypoxia‐induced cardiac remodelling by preserving mitochondrial function, role of SIRT6 signalling[J]. Journal of Cellular and Molecular Medicine, 2024, 28(12): e18407.

[25]Su L, Ni T, Fan R, et al. An attention to the effect of intravitreal injection on the controls of oxygen-induced retinopathy mouse model[J]. Experimental Eye Research, 2024, 248: 110094.

[26]Zhang N, Wei F, Ning S, et al. PPARγ Agonist Rosiglitazone and Antagonist GW9662: Antihypertensive Effects on Chronic Intermittent Hypoxia-Induced Hypertension in Rats[J]. Journal of Cardiovascular Translational Research, 2024: 1-13.

[27]Wang M, Wen W, Chen Y, et al. TRPC5 channel participates in myocardial injury in chronic intermittent hypoxia[J]. Clinics, 2024, 79: 100368.

[28]Nan L, Kaisi F, Mengzhen Z, et al. miR-375-3p targets YWHAB to attenuate intestine injury in neonatal necrotizing enterocolitis[J]. Pediatric Surgery International, 2024, 40(1): 63.

[29]Xie L, Wu Q, Huang H, et al. Neuroregulation of histamine of circadian rhythm disorder induced by chronic intermittent hypoxia[J]. European Journal of Pharmacology, 2025: 177662.

[30]Cai S, Li Z, Bai J, et al. Optimized oxygen therapy improves sleep deprivation-induced cardiac dysfunction through gut microbiota[J]. Frontiers in Cellular and Infection Microbiology, 2025, 15: 1522431.

[31]Liu C, Qu D, Li C, et al. miR‐448‐3p/miR‐1264‐3p Participates in Intermittent Hypoxic Response in Hippocampus by Regulating Fam76b/hnRNPA2B1[J]. CNS Neuroscience & Therapeutics, 2025, 31(2): e70239.

[32]Han J, Wang L, Wang L, et al. 5-Hydroxytryptamine Limits Pulmonary Arterial Hypertension Progression by Regulating Th17/Treg Balance[J]. Biological and Pharmaceutical Bulletin, 2025, 48(5): 555-562.

[33]Lan J, Wang Y, Liu C, et al. Genome-wide analysis of m6A-modified circRNAs in the mouse model of myocardial injury induced by obstructive sleep apnea[J]. BMC Pulmonary Medicine, 2025, 25(1): 158.

*我公司可提供3Q验证，根据客户的特殊应用、特殊需求提供功能定制服务，也可以提供相关的实验服务，详情请来电咨询。

*此介绍及参数为产品基础信息，可能滞后于产品更新，具体参数请与我司联系。

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  动物低氧工作站

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  动物多功能高原环境实验系统

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  动物实验低压氧舱（恒温版）

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  动物实验低压氧舱（标准款）