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Home > PRODUCTS > Respiratory Research > Pulmonary Function Test (PFT)/ Whole-body Plethysmopraphy (WBP)

Pulmonary Function Test System

Product model：

PFT

Detailed introduction:

PFT System is a comprehensive evaluation system for the respiratory and lung function of animals. It can measure airway resis... View details >
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Product Description

PFT System is a comprehensive evaluation system for the respiratory and lung function of animals. It can measure airway resistance, lung compliance, FEV, FVC, FEV0.1/FVC, FEV0.2/FVC, FEF, FRC, EF50, and other indicators. It can be used in mice, rats, guinea pigs, and other animals, other sizes fro larger animal can be customized according to customers' requirements.

During the experiment, the animal needs to be anesthetized and subjected to tracheotomy. The system has a built-in ventilator, which can automatically control the breathing pattern of the animals and coordinate with the lung function test of different modes.

PFT system is widely used in preclinical studies of COPD, pulmonary interstitial disease, pneumonia, pulmonary fibrosis and other diseases, drug evaluation of respiratory pharmacology research, and general pharmacology research.

According to Boyle's law, by detecting the airway and bronchus, the pressure difference between the pleura in the airways of the internal pressure (across lung pressure) to acquire physical indicators such as airflow velocity to airway resistance and lung compliance, and etc.


Features

1. It is used for the comprehensive detection of lung function in experimental animals, such as mice, rats, guinea pigs, and rabbits

2. Anesthesia and tracheotomy are performed

3.  Providing comprehensive lung function analysis, and determine FEV(x), FEF(x), FVC, FEVPEF, MMEF, VT, F, RL, and other parameters in a few minutes

4. Support mechanically assisted ventilation mode and spontaneous breathing mode

5. Adopt imported sensors to ensure the accuracy of data collection

6. Maximum negative pressure up to -10kPa, adjustable negative pressure , can be used for a variety of different animals, such as mice, rats, guinea pigs, rabbits, , and etc.

7. Plethysmopgrahic equipment: transparent PMMA material and aluminum alloy material for easy observation

8. It has the interface of animal intubation drug delivery and blood collection, which can be used for intravenous drug delivery and arterial blood collection of animals

9. It controls the animal to complete the forced lung ventilation function test, such as forced inhalation, forced exhalation, and other actions

10. Able to complete the determination of small animal forced expiratory function for the study of animal models such as COPD

11. The software supports Win7, Win8, Win10

12. It can display smooth breathing waveform output in real-time

13. Allow data recording time adjustment and recovery at any time

14. Real-time continuous data acquisition, record and store the original data, and the software can display the real original breathing waveform in real-time

15. Data can be automatically stored in Excel format for third-party software analysis. Can store curve pictures


Applications

  • Bronchial asthma

  • Chronic obstructive emphysema (COPD)

  • Pulmonary fibrosis

  • Acute and Chronic Respiratory Distress Syndrome (ARDS)

  • Chronic bronchitis

  • Acute or chronic respiratory failure

  • Tracheal dilation and activation experiments

  • Drug evaluation for respiratory pharmacological studies

  • Life science research requiring monitoring of lung function in small animals


    Configuration

Name

Model

Description

Unit

Pulmonary Function Test System

PFT-M

For mice

Set

Pulmonary Function Test System

PFT-MR

For mice, rats, guinea pigs

Set


*Our company can provide customized services according to customers' special applications, requirements, as well as experimental services. Please kindly contact us for more information.